Scanning Reflective on the creo iqsmart2
Preparing to Scan
It's imperative to the quality of the scan to take your time and clean up the glass bed of the scanner before you scan. Wipe the bed with an anti-static cloth to remove dust; if there are finger prints or other smudges, spray a paper wipe with glass cleaner and gently clean the scan bed. Do not apply the glass cleaner directly on the scanner.
Once the scan bed is clean, turn on the scanner using the power button on the top right. Place your media face down on the bed of the scanner, at least 1/4 inch away from any edge.
Scanning

Now, you'll need to give the scanner some information about what you're scanning and how you'd like it to end up. First, tell the scanner where on the bed your media is, to avoid a long preview. You can resize the bounding box by dragging on the lower right corner. The window is analogous to the geography of the scan bed:

The previous step is not absolutely necessary, but will save you some time.
Next, use the Setup Dialog to tell the software how you'd like it to scan. Here are the settings for what might be a typical reflective scan workflow:

Crop Size: denotes the size of the area being scanned (in this case 8.46 x 11.89"); this is probably larger than your actual media so take that into account when you are doing your calculations
Scale: how much larger or smaller you want your final scan to be (in this case, 150%).
Resolution: the resolution of your final scan.
Output Size: calculated using the scale and resolution values you entered (12.70 x 17.83").
Input Profile: automatically populated, but you can choose others.
The rest of the settings should remain at their defaults unless you wish to change them.
Once you have your settings dialed in, hit the preview button on the top menu
bar:
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After a few minutes of activity, your preview appears:

A bounding box is, by default, present around your scan area. Using the corner and side handles, resize the bounding box to the exact specifications of your image. You can scan more than one image by pressing Command-D (or Edit > Duplicate Crop) to give you a second bounding box for another part of the bed.
When you are satisfied with your crop, select Scan > Scan > All crops. You will be prompted to save them before the scan starts, so be sure and note where you are saving them, as well as what names you are giving them. The default is usually SCAN_1_1. Be sure and add .tif to the end if you want to see it on a Windows machine.
A queue displays on the screen, showing the progress of the the scan. If you
have several items set to scan, you can walk away while the scanner works.
Be sure to transfer your files to the network or a jump drive, as it's never
a guarantee they will be there after the day they were scanned.